Apneusis responding to buspirone in multiple sclerosis.

نویسندگان

  • R J O'Sullivan
  • I G Brown
  • M P Pender
چکیده

Apneusis is a disturbance of respiratory rhythm characterized by severely prolonged inspiratory effort, and is caused by bilateral lesions in the dorsal pons. In humans it is most commonly caused by pontine infarction and has rarely been reported in multiple sclerosis (MS). Here we report on a patient with MS who developed episodic apneusis which responded to treatment with buspirone, a serotonin type 1A receptor agonist.

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Buspirone treatment for apneustic breathing in brain stem infarct.

We report a case of brainstem infarction resulting in apneustic breathing, which was alleviated with buspirone. We discuss apneusis, review the literature, and speculate about the benefit of serotonin 1A receptor agonists in the treatment of apneusis and other respiratory disorders.

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عنوان ژورنال:
  • Multiple sclerosis

دوره 14 5  شماره 

صفحات  -

تاریخ انتشار 2008